Cyclobenzaprine and dogs

Muscle relaxers for dogs are used to reduce muscle pain, inflammation, and general stiffness that cannot be treated with natural at-home remedies. You can use over the counter muscle relaxants ...

Cyclobenzaprine hydrochloride relieves skeletal muscle spasm of local origin without interfering with muscle function. It is ineffective in muscle spasm due to central nervous system disease. Controlled clinical studies show that cyclobenzaprine hydrochloride improves the signs and the symptoms of skeletal muscle spasm.Cyclobenzaprine is a muscle relaxer that may help reduce muscle pain and discomfort. One option to treat muscle pain and discomfort is cyclobenzaprine. In this video, learn basic tips for taking this muscle relaxant to improve your treatment outcomes. If you have more questions, ask your pharmacist or the healthcare provider who prescribed the ...What is Flexeril and why would a dog need to take it? Flexeril is a medication commonly prescribed to humans as a muscle relaxant. However, it is also used in veterinary medicine as a treatment for conditions that cause muscle spasms or stiffness in dogs. These can include chronic pain, back injuries, arthritis, or muscle strains.flexeril by Good Dog - 2015-12-22 08:12:45 I don't know anything about it "causing" bradycardia. However, I tried taking it and it makes me feel terrible. ... Your question interests me because I've taken both Flexeril and Baclofen alternating between the two for 9 years daily. I also take Tramadol daily for chronic back pain and muscle spasms. The main types are: Drug-drug interaction. This is when a medication reacts with one or more other drugs. For example, taking a cough medicine ( antitussive) and a drug to help you sleep (sedative ... Salicylates- Most pain-relief creams contain salicylates, which is basically aspirin. Both dogs and cats are moderately to severely sensitive to this substance, but it is particularly dangerous to cats. This is the active ingredient in Aspercreme, Bengay, HEET, Icy Hot, etc. The oil of wintergreen also has a high concentration of salicylates.Applies to: nadolol and cyclobenzaprine. Nadolol and cyclobenzaprine may have additive effects in lowering your blood pressure. You may experience headache, dizziness, lightheadedness, fainting, and/or changes in pulse or heart rate. These side effects are most likely to be seen at the beginning of treatment, following a dose increase, or when ...

Flexeril is the brand name for a prescription drug called cyclobenzaprine. Flexeril can be used to treat muscle spasms, muscle pain, and stiffness from sprains and other injuries. Flexeril is a central nervous system (CNS) depressant and muscle relaxer. CNS depressants have a calming or relaxing effect on the body and brain, which they achieve ...Cyclobenzaprine, often used in management of acute muscle spasms, is almost completely absorbed after an oral dose, with peak plasma levels in 3–8 hr. It has extensive liver metabolism and undergoes enterohepatic recirculation. The most common signs seen in dogs and cats include depression and ataxia.Dogs and cats at greatest risk for developing side effects from NSAID therapy are those that are dehydrated, on concomitant diuretic therapy, have recently been treated with a corticosteroid, or ...In humans, the oral bioavailability of cyclobenzaprine is between 33 and 55% (9, 13, 14) and peak plasma levels may not be reached for 3 to 8h after ingestion ( 11, 12). Hucker …cyclobenzaprine traMADol. Using narcotic pain or cough medications together with other medications that also cause central nervous system depression can lead to serious side effects including respiratory distress, coma, and even death. Talk to your doctor if you have any questions or concerns. Your doctor may be able to prescribe alternatives ...Applies to: cyclobenzaprine and venlafaxine. Using cyclobenzaprine together with venlafaxine can increase the risk of a rare but serious condition called the serotonin syndrome, which may include symptoms such as confusion, hallucination, seizure, extreme changes in blood pressure, increased heart rate, fever, excessive sweating, shivering or ...A rapid and sensitive liquid chromatography-tandem mass spectrometry method was developed and validated for the quantification of cyclobenzaprine in dog plasma. After extracted with organic solvent, post-treatment samples were separated on an Agela C18 column interfaced with a triple quadrupole tandem mass spectrometer in positive ...

Muscle relaxers for dogs are used to reduce muscle pain, inflammation, and general stiffness that cannot be treated with natural at-home remedies. You can use over the counter muscle relaxants ...The most common side effects of Robaxin and Flexeril are drowsiness, dizziness, and headache. Flexeril may be associated with more drowsiness compared to Robaxin. Because of its anticholinergic properties, Flexeril can also cause dry mouth. Both Robaxin and Flexeril can cause some degree of fatigue or nausea.2. Dogs do not tolerate cyclobenzaprine very well so there is a possibility of adverse effects, these could include depression, inability to walk, weakness and a low heart rate. Of course if any symptoms do set in then you should take Angel to an ER vet without delay.It helps relieve pain, stiffness, and discomfort caused by strains, sprains, or injuries to your muscles. However, this medicine does not take the place of rest ...

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Applies to: bisoprolol and cyclobenzaprine. Bisoprolol and cyclobenzaprine may have additive effects in lowering your blood pressure. You may experience headache, dizziness, lightheadedness, fainting, and/or changes in pulse or heart rate. These side effects are most likely to be seen at the beginning of treatment, following a dose increase, or ...... Dog Kibble for Muscle, Robaxin Muscle Relaxer in Dogs ... #dogsoftiktok #dog #dogsvideo #dogs #fyp #fyp ... cyclobenzaprine #musclerelaxer #backpaintreatments # ...Cyclobenzaprine (not available in the UK and Europe) helps relieve the pain of muscle spasms caused by these types of injury. It works by relaxing the muscles, which reduces pain and discomfort and makes movement easier. Cyclobenzaprine is used in addition to rest and physiotherapy to help you recover from the injury.Applies to: nadolol and cyclobenzaprine. Nadolol and cyclobenzaprine may have additive effects in lowering your blood pressure. You may experience headache, dizziness, lightheadedness, fainting, and/or changes in pulse or heart rate. These side effects are most likely to be seen at the beginning of treatment, following a dose increase, or when ...

Just give it straight or mix in a cup of hot water and add 5-10 drops of lemon. You can dose your dog or cat 2-3 times/ day, for 7-10 days. Many pets feel symptomatically better within the day. Coconut Oil. Coconut oil has an array of uses. It's good for digestion, brain health and is very soothing on the throat.Dog grooming industry isn’t exactly a new concept. Here is how scenthound is pioneering in a full array of dog grooming services. Dog grooming isn’t exactly a new concept. But Scen...Serious side effects may be more likely in older adults. Common Flexeril side effects may include: drowsiness, tiredness; headache, dizziness; dry mouth; or. upset stomach, nausea, constipation. This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects.Corpus ID: 43110910; Physiological disposition and metabolism of cyclobenzaprine in the rat, dog, rhesus monkey, and man. @article{Hucker1978PhysiologicalDA, title={Physiological disposition and metabolism of cyclobenzaprine in the rat, dog, rhesus monkey, and man.}, author={Howard B. Hucker and S. C. Stauffer and A J Balletto and S D White and Anthony G. Zacchei and Byron H. Arison}, journal ...Jan 11, 2023 · Wondering if Cyclobenzaprine is safe for your dog? Our comprehensive guide covers the uses, dosages, and risks to keep your dog healthy. The first thing you'll want to do when your pupper gets sick is try to fix the problem at home. Cyclobenzaprine HCl USP, 5 mg is supplied as a 5 mg tablet for oral administration. ... Pharmacological studies in animals showed a similarity between the effects of cyclobenzaprine and the structurally related tricyclic antidepressants, including reserpine antagonism, norepinephrine potentiation, potent peripheral and central anticholinergic ...Compounded ophthalmic cyclosporine drops have been used commonly in 1.0-2.0% concentrations in corn oil when Optimmune® was either commercially unavailable or owners were physically unable to apply an ointment. An aqueous suspension of 0.05% cyclosporine (Restasis®) was developed by Allergan Pharmaceuticals for treatment of KCS in human patients.Oct 15, 2023 ... Methocarbamol is a muscle relaxant commonly used in veterinary medicine to provide relief from muscle pain in dogs. One of the key benefits of ...

cyclobenzaprine food. Applies to: cyclobenzaprine. Alcohol can increase the nervous system side effects of cyclobenzaprine such as dizziness, drowsiness, and difficulty concentrating. Some people may also experience impairment in thinking and judgment. You should avoid or limit the use of alcohol while being treated with cyclobenzaprine.

Cyclobenzaprine targets the root cause of pain, reducing muscle spasms and relaxing tense muscles. Ibuprofen, with its anti-inflammatory properties, further enhances pain relief by reducing inflammation in the affected area. Together, these medications form a potent duo to combat pain and discomfort.If you give your dog 1.1 mg per 2.2 pounds of body weight, it will not have any toxic effect. However, your dog can have some side effects like vomiting, drooling or heartbeat becoming high. The truly toxic dosage of Flexeril is 12.2 mg per 2.2 pounds of your dog's body weight. #2.Introduction: The objective of this case series is to describe the clinical signs and outcome of cyclobenzaprine ingestion in two dogs treated with intralipid emulsion (ILE) and supportive care. Case or series summary: Two dogs presented for evaluation of cyclobenzaprine ingestion. A 4-year-old female spayed Rat Terrier (dog 1) presented …A 4-year-old female spayed Rat Terrier (dog 1) presented within 4 h of ingestion of cyclobenzaprine (between 9.7 and 25.9 mg/kg). The dog experienced abnormal behavior, agitation, tremors ... I am sorry to hear that your pup ingested a 10mg Cyclobenzaprine (Flexeril) pill. This drug is not well tolerated in dogs and is absorbed very quickly. Once it has been more then 1 hour it is likely too late to retrieve by inducing vomiting. The truly toxic dose is 12 mg/kg (12mg per 2.2 pounds of body weight). PubMed Cyclosporine is a medication that targets the immune system and is used to treat atopic (allergic) dermatitis in dogs and cats. Cyclosporine is given by mouth, in the form of a capsule for dogs and a liquid suspension for cats. The most common side effects of cyclosporine are gastrointestinal side effects, such as vomiting, diarrhea, and decreased appetite (anorexia). Cyclosporine should be ...cyclobenzaprine traMADol. Using narcotic pain or cough medications together with other medications that also cause central nervous system depression can lead to serious side effects including respiratory distress, coma, and even death. Talk to your doctor if you have any questions or concerns. Your doctor may be able to prescribe alternatives ...

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Applies to: Restoril (temazepam) and Flexeril (cyclobenzaprine) Using temazepam together with cyclobenzaprine may increase side effects such as dizziness, drowsiness, confusion, and difficulty concentrating. Some people, especially the elderly, may also experience impairment in thinking, judgment, and motor coordination.Cyclobenzaprine has not been classified as an addictive drug because it is completely away from that class of drugs; it has no relationship with the narcotic family. Although, Cyclobenzaprine is not considered to be a narcotic drug, it is still addictive. Common side effects of cyclobenzaprine include: Dizziness, drowsiness, dry mouth, fatigue and Constipation.Cyclobenzaprine hydrochloride, USP is a white to off-white, odorless, crystalline powder with the molecular formula C 20 H 21 N•HCl and a molecular weight of 311.85. It has a melting point between 215°C to 219°C and a pKa of 8.47. It is freely soluble in water, in alcohol, and in methanol, sparingly soluble in isopropanol, slightly soluble ...cyclobenzaprine food. Applies to: cyclobenzaprine. Alcohol can increase the nervous system side effects of cyclobenzaprine such as dizziness, drowsiness, and difficulty concentrating. Some people may also experience impairment in thinking and judgment. You should avoid or limit the use of alcohol while being treated with cyclobenzaprine.Methocarbamol is a medication used in the management and treatment of acute musculoskeletal pain. It is in the skeletal muscle relaxant class of medications. This activity reviews the indications, mechanism of action, and contraindications for methocarbamol as an option in the multimodal treatment of acute musculoskeletal pain. This activity will also underscore critical factors to consider ...Methocarbamol is a muscle relaxer used to treat skeletal muscle spasms in dogs that may be caused by trauma, inflammation, infection, or toxicity. This drug only affects signals that are relayed to skeletal muscle, so methocarbamol doesn’t affect the smooth muscles present in the intestines, the bladder, and other parts of the body.of cyclobenzaprine in dog Wenhong Yu, Xiaojing Yang, Wenwen Sui, Haiyan Xu, Xinyi Luan, Xiangjun Wang, Yi Jin, Bo Yuan* Shenyang Pharmaceutical University, No. 103, Wenhua Road, Shenyang 110016, ChinaApplies to: cyclobenzaprine. Alcohol can increase the nervous system side effects of cyclobenzaprine such as dizziness, drowsiness, and difficulty concentrating. Some people may also experience impairment in thinking and judgment. You should avoid or limit the use of alcohol while being treated with cyclobenzaprine. ….

Two dogs presented for evaluation of cyclobenzaprine ingestion. A 4-year-old female spayed Rat Terrier (dog 1) presented within 4 h of ingestion of cyclobenzaprine (between 9.7 and 25.9 mg/kg). The dog experienced abnormal behavior, agitation, tremors, tachycardia, and hypertension. There were no significant clinicopathological abnormalities.I've never taken cyclobenzaprine with opiates but on its own, cyclobenzaprine has no recreational value. Not much recreational value might make you sleep better but that’s about it. Like other dude said almost no recreational value at all if any. Cyclo sucks alone. It's really not even much better mixed with opiates.To date, there are no known publications on cyclobenzaprine ingestion in veterinary medicine. This case series describes the clinical signs and successful …ALPRAZolam cyclobenzaprine. Applies to: Xanax (alprazolam) and cyclobenzaprine. Using ALPRAZolam together with cyclobenzaprine may increase side effects such as dizziness, drowsiness, confusion, and difficulty concentrating. Some people, especially the elderly, may also experience impairment in thinking, judgment, and motor coordination.The recommended adult dose for most patients is one (1) cyclobenzaprine hydrochloride extended-release 15 mg capsule taken once daily. Some patients may require up to 30 mg/day, given as one (1 ... 3 DOSAGE FORMS AND STRENGTHS. Extended-release capsules in the following strengths: 15 mg: Capsules are orange/orange and are embossed in blue ink ...1 interaction. Contraindicated. cyclobenzaprine + phenelzine. contraindicated w/in 14 days of phenelzine use: combo may incr. risk of serotonin syndrome, CNS depression, psychomotor impairment, hyperpyretic crisis, seizures, severe constipation, paralytic ileus, urinary retention (additive effects) potassium chloride.Common side effects of Skelaxin vs. Flexeril. Both drugs can be very sedating. Skelaxin's most common side effects are drowsiness, dizziness, headache, irritability, nausea, vomiting, and stomach upset. The most common side effects of Flexeril are drowsiness, dizziness, headache, and dry mouth. With either drug, an allergic reaction is rare ...Applies to: cyclobenzaprine. Alcohol can increase the nervous system side effects of cyclobenzaprine such as dizziness, drowsiness, and difficulty concentrating. Some people may also experience impairment in thinking and judgment. You should avoid or limit the use of alcohol while being treated with cyclobenzaprine. Quick Contact Tel: 001-735-1688 Fax: 001-164-6488 Email: info ( at ) compbdhany.com Cyclobenzaprine is used to help relax certain muscles in your body. It helps relieve pain, stiffness, and discomfort caused by strains, sprains, or injuries to your muscles. However, this medicine does not take the place of rest, exercise or physical therapy, or other treatment that your doctor may recommend for your medical problem. ... Cyclobenzaprine and dogs, CYCLOBENZAPRINE (sye kloe BEN za preen) treats muscle spasms. It works by relaxing your muscles, which reduces muscle stiffness. It belongs to a group of medications called muscle relaxants. This medicine may be used for other purposes; ask your health care provider or pharmacist if you have questions. COMMON BRAND NAME(S): Fexmid, Flexeril, Applies to: cyclobenzaprine and Cymbalta (duloxetine) Using cyclobenzaprine together with DULoxetine can increase the risk of a rare but serious condition called the serotonin syndrome, which may include symptoms such as confusion, hallucination, seizure, extreme changes in blood pressure, increased heart rate, fever, excessive sweating ..., Some dosage forms listed on this page may not apply to the brand name Flexeril. Applies to cyclobenzaprine: oral capsule extended release, oral suspension, oral tablet. Serious side effects of Flexeril. Along with its needed effects, cyclobenzaprine (the active ingredient contained in Flexeril) may cause some unwanted effects. Although not all ..., Customer: I dropped a cyclobenzaprine and my dog ingested it. He is 1 year and 60 lbs. His name is*****: I'll do all I can to help. The Expert will know if Blu will be able to digest that. Is there anything else important you think the Veterinarian should know about Blu? Customer: Nothing. Just want to know what signs to look for and if he will ..., Using buPROPion with alcohol may increase the risk of uncommon side effects such as seizures, hallucinations, delusions, paranoia, mood and behavioral changes, depression, suicidal thoughts, anxiety, and panic attacks. On the other hand, sudden withdrawal from alcohol following regular or chronic use can also increase your risk of seizures ..., Cyclobenzaprine is FDA-approved as an adjunct to rest for the treatment of muscle spasms associated with acute, painful musculoskeletal conditions. Cyclobenzaprine is a part of a group of medications referred to as cyclical antidepressants. Cyclobenzaprine is a tricyclic amine salt that works in the central nervous system (CNS) as a depressant that reduces muscle hyperactivity. These cyclical ..., Objective. To determine the effects of bedtime very low dose (VLD) cyclobenzaprine (CBP) on symptoms and sleep physiology of patients with fibromyalgia (FM), unrefreshing sleep, and the α-nonREM sleep electroencephalographic (EEG) anomaly at screening. Methods. Of 37 patients with FM in the screened population, 36 were randomized and treated in this 8-week, double-blind, placebo-controlled ..., Based on the findings, Cyclobenzaprine HCl should be used with caution in subjects with mild hepatic impairment starting with the 5 mg dose and titrating slowly upward. Due to the lack of data in subjects with more severe hepatic insufficiency, the use of Cyclobenzaprine HCl in subjects with moderate to severe impairment is not recommended., The use of cyclobenzaprine reported in the literature in dogs is very limited. Two studies evaluated oral bioavailability and excretion of cyclobenzaprine in dogs. The first study administered a dose of 30mg/kg by mouth once a day for 3days to Beagle dogs ( 2). Neither study evaluated for nor reported complications associated with, Cyclobenzaprine hydrochloride extended-release capsules are indicated as an adjunct to rest and physical therapy for relief of muscle spasm associated with acute, painful musculoskeletal conditions. Improvement is manifested by relief of muscle spasm and its associated signs and symptoms, namely, pain, tenderness, and limitation of motion., What is Flexeril and why would a dog need to take it? Flexeril is a medication commonly prescribed to humans as a muscle relaxant. However, it is also used in veterinary medicine as a treatment for conditions that cause muscle spasms or stiffness in dogs., A rapid and sensitive liquid chromatography-tandem mass spectrometry method was developed and validated for the quantification of cyclobenzaprine in dog plasma. After extracted with organic solvent, post-treatment samples were separated on an Agela C18 column interfaced with a triple quadrupole tandem mass spectrometer in positive ..., Cyclobenzaprine for dogs: Treating muscle spasms and severe pain. Check Details. Pin on Casey girl. Check Details. CYCLOBENZAPRINE HYROCHLORIDE (H.J. Harkins Company, Inc.): FDA Package. Check Details. Erowid Cyclobenzaprine (Flexeril) Vault. Check Details. Buy Cyclobenzaprine ( Generic Flexeril ) online in US pharmacy with COD., Applies to: cyclobenzaprine and Imodium (loperamide) Using loperamide together with cyclobenzaprine may increase side effects such as dizziness, drowsiness, and difficulty concentrating. You should avoid or limit the use of alcohol while being treated with these medications. Also avoid activities requiring mental alertness such as driving or ..., Cyclobenzaprine is often used for the management of acute muscle spasms in cats and dogs. Side Effects: The most common side effects seen in dogs and cats include depression and ataxia. Red Rx icon indicating prescription. Prescription Required. Please enter pet & vet info at check out ..., Applies to: Benadryl (diphenhydramine) and cyclobenzaprine. Using diphenhydrAMINE together with cyclobenzaprine may increase side effects such as drowsiness, blurred vision, dry mouth, heat intolerance, flushing, decreased sweating, difficulty urinating, abdominal cramping, constipation, irregular heartbeat, confusion, and memory problems., Using cyclobenzaprine together with pramipexole may increase side effects such as dizziness, drowsiness, confusion, and difficulty concentrating. Some people, especially the elderly, may also experience impairment in thinking, judgment, and motor coordination. You should avoid or limit the use of alcohol while being treated with these ..., Dogs should never take Flexeril, according to the Merck Veterinary Manual. The veterinary manual states that Flexeril, also known as cyclobenzaprine, is toxic to canines and can cause severe reactions. The Merck Veterinary Manual states that symptoms of Flexeril poisoning in dogs include vomiting, weakness, seizures and hypothermia., Pharmacological studies in animals showed a similarity between the effects of cyclobenzaprine and the structurally related tricyclic antidepressants, including reserpine antagonism, norepinephrine potentiation, potent peripheral and central anticholinergic effects, and sedation. ... Cyclobenzaprine Hydrochloride Tablets USP, 5 mg are yellow ..., The most common side effects of Robaxin and Flexeril are drowsiness, dizziness, and headache. Flexeril may be associated with more drowsiness compared to Robaxin. Because of its anticholinergic properties, Flexeril can also cause dry mouth. Both Robaxin and Flexeril can cause some degree of fatigue or nausea., Cyclobenzaprine, often used in management of acute muscle spasms, is almost completely absorbed after an oral dose, with peak plasma levels in 3–8 hr. It has extensive liver metabolism and undergoes enterohepatic recirculation. The most common signs seen in dogs and cats include depression and ataxia. Are muscle relaxers safe for dogs? …, Cyclobenzaprine caused slight to moderate increase in heart rate in animals. Pharmacokinetics. Estimates of mean oral bioavailability of cyclobenzaprine range from 33% to 55%. Cyclobenzaprine exhibits linear pharmacokinetics over the dose range 2.5 mg to 10 mg, and is subject to enterohepatic circulation. It is highly bound to plasma …, Applies to: cyclobenzaprine and Cymbalta (duloxetine) Using cyclobenzaprine together with DULoxetine can increase the risk of a rare but serious condition called the serotonin syndrome, which may include symptoms such as confusion, hallucination, seizure, extreme changes in blood pressure, increased heart rate, fever, excessive sweating ..., Methocarbamol is a prescription medication FDA approved for veterinary use in dogs, cats, and horses. Methocarbamol is available as 500 mg tablets. The usual dose to treat muscle spasms in dogs and cats is 20 to 30 mg per lb every 8 to 12 hours on the first day, then 10 to 30 mg per pound every 8 to 12 hours. Cyclobenzaprine., Cyclobenzaprine (Flexeril) Tizanidine (Zanaflex) Oxazepam; Carisoprodol (Soma) Baclofen; Metaxalone (Skelaxin) There are so many skeletal muscle relaxants. And many are actually just as dangerous for dogs (if not more so) than popular pain killers or NSAIDS. What's absolutely certain is this: Antispasmodic drugs could put your dog in harm's ..., 1. Introduction. Cyclobenzaprine, 3-(5H-dibenzo[a,d]cyclohepten-5-ylidene)-N,N-dimethyl-1-propanamine, is classified as a skeletal muscle relaxant and is one of the most commonly prescribed agents for the management of musculoskeletal pain [1, 2].It was first synthesized in 1961, and, in 1977, the 10 mg dose was approved as an adjunct to rest and physical therapy for the relief of muscle spasm ..., Cyclobenzaprine hydrochloride has active ingredients of cyclobenzaprine hydrochloride. It is used in muscle spasms. Currently, eHealthMe is studying from 8,107 Cyclobenzaprine hydrochloride users. Check the latest outcomes. Number of Ciprofloxacin and Cyclobenzaprine hydrochloride reports submitted per year:, Based on the findings, Cyclobenzaprine HCl should be used with caution in subjects with mild hepatic impairment starting with the 5 mg dose and titrating slowly upward. Due to the lack of data in subjects with more severe hepatic insufficiency, the use of Cyclobenzaprine HCl in subjects with moderate to severe impairment is not recommended., eye redness, lightheadedness, dizziness, spinning sensation, drowsiness, sleep problems (insomnia), stuffy nose, itching, or. rash, especially during the first few days as your body adjusts to this medication., Feb 12, 2024 · Two dogs presented for evaluation of cyclobenzaprine ingestion. A 4-year-old female spayed Rat Terrier (dog 1) presented within 4 h of ingestion of cyclobenzaprine (between 9.7 and 25.9 mg/kg). The dog experienced abnormal behavior, agitation, tremors, tachycardia, and hypertension. There were no significant clinicopathological abnormalities. , numbness, tingling, pain, or weakness in hands or feet. pounding heartbeat. problems in speaking. trembling. trouble sleeping. unpleasant taste or other taste changes. unusual muscle weakness. unusual tiredness. Other side effects not listed may also occur in …, I am sorry to hear that your pup ingested a 10mg Cyclobenzaprine (Flexeril) pill. This drug is not well tolerated in dogs and is absorbed very quickly. Once it has been more then 1 hour it is likely too late to retrieve by inducing vomiting. The truly toxic dose is 12 mg/kg (12mg per 2.2 pounds of body weight)., Cyclobenzaprine hydrochloride is a white, crystalline tricyclic amine salt with the empirical formula C20H21N HCl and a molecular weight of 311.9. It has a melting point of 217oC, and a pK a of 8.47 at 25oC. It is freely soluble in water and alcohol, sparingly soluble in isopropanol, and insoluble in hydrocarbon solvents.