How long can i keep trimix in a syringe

Use the needles, syringe, alcohol swabs, and vials only 1 time then safely throw away the supplies and any unused solution in a puncture resistant container (See "Dispose of your used CAVERJECT syringe and needle" at the end of these instructions). Ask your healthcare provider or pharmacist where you can get a puncture resistant or sharps ...

How long can i keep trimix in a syringe. Hold the syringe system with the needle pointing upward. ... Long-term carcinogenicity studies have not ... discarded since each syringe can only be used one time.

Thus, this preparation was proven to be stable for 55 days and this allows the fabrication of ready-to use syringes of Trimix. These syringes could be prepared under aseptic conditions and so supply to the patients a quality treatment also allowing them to improve their living conditions. ... Long-term stability of dexamethasone and alizapride ...

How long do I keep Trimix in a syringe? The shelf life of Trimix in a syringe depends on several factors, including the composition of the solution, storage conditions, and the presence of bacteria or other contaminants. Generally, Trimix should be used within 24 hours of being drawn up into a syringe and should be discarded if there is any ...By long term I mean 3 years or longer. ... In all the years of my usage of Trimix, I can count on1 hand the times where I discovered I injected myself incorrectly and gained no benefits (much to my wife's dismay), and one time when I was more high than I thought I might be and, withdrawing the syringe from the left side of my penis, my hands ...Q21. How can I make it easier to withdraw the medication from the upside-down glass vial? A21. Before filling the syringe, pull back on the plunger to fill the syringe with air in a volume roughly equivalent to the amount of fluid you are planning to inject. After the syringe is filled with air, push the- Syringe C. Keep the Trimix cold by returning the botle to the refrigerator, or by placing the botle in a cup of ice. 2. PREPARE THE SYRINGE A. Wipe the rubber top of the vial with an alcohol pad. B. Ater removing the cap of the needle, pull the plunger back to the desired dosage, illing this volume with air. Use a new needle and syringe each ime.Having read some articles about the rate of decay of trimix unrefrigerated, I did some of my own testing. Back in 2015, I pre-filled about 12 syringes with various doses of Trimix, for example my normal dose plus 10%, + 20%, +30% etc., and left these syringes unrefrigerated at my average summer room temperature of about 25° (77F) for up to 5 ...As far as your trimix, don't continue to freeze and thaw, best to just keep refrigerated, or make up all your syringes, freeze them, than thaw one as needed. Good luck. I must say, my reaction reaction after injection of trimix is within minutes I fill a warmth, then a gradual expansion of my penis.To date, there is no definitive evidence to suggest how long 1 mg/mL epinephrine prefilled syringes are stable or sterile, as the current research has only indicated stability and sterility for up to 3 months. ... If used, epinephrine prefilled syringes should be stored with sealed caps in light-blocking containers that prevent the syringe ...

Trimix injections do not conflict with Shockwave and other ED treatment programs, so men are free to use Trimix for a reliable erection even as they explore other, long-lasting, treatment options. For some men, Trimix injections are a good long-term solution. For others Trimix may be a temporary method to permit intimacy. *Results may vary.2.5mg, 5mg recommended for daily use. BiMix is a prescription treatment for impotence, also known as erectile dysfunction (ED), a condition impacting over 18 million men in the United States. For many patients struggling with erectile dysfunction who have tried "everything else" to produce and maintain an erection, this medication offers ...Trimix users and MDs : Trimix went from 100% efficacy to 0% overnight. Hi guys, I've been using trimix for a little under a month. Was working absolutely perfectly, until a few days ago (Dec 26th), it just stopped working somehow. It stopped totally. Trimix might even make it more difficult now to achieve an erection than without.The recommended freezer storage time for ham varies depending on the type. Fully cooked ham can be frozen for 2 to 3 months, while uncooked fresh ham can safely be stored for 6 to 8 months. Cured ham has a longer freezer life and can be stored for up to a year. 4.1st injection: try 0.1ml (or 10 units as marked on the side of the syringe). If this is not successful, do not give yourself a second injection. Wait a minimum ...can be treated. You can minimize the risk of getting Peyronie’s by learning to inject correctly. Q11. Are there any medications I can take to further reduce the risk of getting Peyronie’s Disease? A11. Yes, pentoxifylline 2-3 pills a day may halt the development of Peyronie’s Disease. Q12. Can massaging the site reduce the chance of ...Demonstration on reconstituting Trimix. Scroll down to watch the video. Any questions, email us at hello@ ... the powder and Bacteriostatic Water. Wipe the tops with the alcohol swabs and let dry. Using the provided mixing syringe tighten the needle to the hub then pull back the plunger to the amount directed, usually 5ml/cc, and insert the ...

The injections available on prescription through our compounding laboratory include: (1) BIMIX – various combinations containing two commonly used vasodilators for ED. (2) TRIMIX – Triple combination therapy was first introduced in 1991 by Bennett and his colleagues who demonstrated a success rate of TriMix of 92% in 116 patients using this ...This helps your penis get hard and stay that way long enough for sex. ... can't see your penis due to your weight. Tell ... Hold the syringe between your thumb ...The sooner you begin to plan, the better. By clicking "TRY IT", I agree to receive newsletters and promotions from Money and its partners. I agree to Money's Terms of Use and Priva...This was a comprehensive study and, in summary, the principal findings were as follows: Bimix, Trimix and Alprostadil can be frozen at -20degC for 6 months and then thawed to room temperature (23degC) with no loss greater than 5% of any of the drugs. They tested up to 4 freeze/thaw cycles with no adverse effects.For instance, at Invigor Medical, a single Trimix vial is available for $249, while two vials can be purchased for $349. Regarding individual doses, the cost typically falls within the range of $1.50 to $3.50 per dose. If Trimix is administered in a clinical setting, anticipate paying between $20.00 and $40.00.Posted 7/27/2015 6:32 AM (GMT -8) I have never traveled by air with Trimix or syringes. But I have traveled with a VED. I just put it in my checked baggage. I would do the same with the Trimix and the cooling bags. In fact, wrapping it in clothes adds to the insulation and keeps it colder, longer.

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In case if you are supposed to use the medication immediately, the best option is to keep your injections in the refrigerator providing temperatures ranging from …This section is just a basic overview of my experience using Trimix. Trimix is an injectable drug for the treatment of erectile dysfunction. Trimix is composed of three drugs: alprostadil, phentolamine, and papaverine. The doctor can vary the amounts of the levels of the individual drugs in the prescription.How long raw chicken lasts in the freezer also depends on whether it is a whole bird, cut into parts, raw or cooked: Whole chicken: up to 1 year. Chicken pieces, such as chicken cutlets: up to 9 months. Ground chicken: 3 to 4 months. Fully cooked chicken sausage: 1 to 2 months. Chicken sausage purchased frozen: 1 to 2 months.My advice is needle no larger than 29ga and no longer than 1/2", unless you are lucky enough to be hung like a horse. Update- I injected trimix last night on my own for the first time, .33 cc of trimix with a .5 cc syringe with a 30g x 5/16 needle and it work very well, no pain at all and was quick.Meat Injector, Stainless Steel Marinade Injector Flavor Syringe Kit with 2-oz Measurement Window for Smoker Food BBQ Grill, Cooking Turkey Chicken Steak Beef Brisket Pork-Chops, 3 Meat Needles 4.6 out of 5 starsKeep the needle tip below the level of the liquid and pull back on the syringe plunger until all the diluent is removed from vial. Figure J: Remove the liquid from the vial. Step 9. Push the syringe plunger to the 1mL mark on the syringe. This will remove air and extra liquid back into vial.

Having read some articles about the rate of decay of trimix unrefrigerated, I did some of my own testing. Back in 2015, I pre-filled about 12 syringes with various doses of Trimix, for example my normal dose plus 10%, + 20%, +30% etc., and left these syringes unrefrigerated at my average summer room temperature of about 25° (77F) for up to 5 ...Trimix injections do not conflict with Shockwave and other ED treatment programs, so men are free to use Trimix for a reliable erection even as they explore other, long-lasting, treatment options. For some men, Trimix injections are a good long-term solution. For others Trimix may be a temporary method to permit intimacy. *Results may vary.Feb 1, 2024 · Remove the needle from the bottle, holding the barrel of the syringe. Gently swirl the bottle to mix the powder into the solution, turning it upside down to wet all the powder in the bottle. Use the mixture within 24 hours of mixing it. Follow the directions below, “How to draw your dose into the syringe." 3. First, holding the syringe upright so the needle faces the sky, pull the plunger of the syringe back past the dose you were told to inject. Next, push the plunger back up until the top of the plunger (the thin black line closest to the needle) is at the dose you were told to inject. Penile Injection Therapy 3/16. 4.Trimix does lose some of its oomph if you keep it in the fridge too long but the only danger that out-of-date trimix represents is that the dose a man using old drugs would need might send him to the emergency room if he injects the same amount from a fresh bottle. Thurman. Regular Member. Joined : Aug 2014.You can store your breastmilk for up to 3 days where you don’t know the temperature, or it runs between 5-10°C. Breastmilk can be stored for 5 days in a fridge running at 4°C or lower.*. *One study has shown fresh breastmilk can be used for up to 8 days when the fridge temperature is kept stable at 4°C or below.While the exact shelf life of homemade trimix in the refrigerator may vary depending on various factors, such as gas leakage and degradation, following best practices for storage can help maximize its longevity. Remember to always consult the manufacturer's recommendations for the specific gases and containers you are using and regularly check ...If you don't want to lose a bit you should leave a several-unit bubble in the syringe and freeze them needle-up. I figured all this out when I noticed that 35 units of frozen trimix turned into 32 units when re-thawed. SUCCESS WITH FROZEN TRIMIX!I am 38 months out from DaVinci RP and have been using Trimix since month 8.Folks, on August 13th I'll be celebrating my first anniversary of participating in online conversation. It also happens to be my birthday. When I initially posted to a bulletin board I was looking to spread the gospel of penile injections for ED, and I thought that would be the end of it. My husband had had an RP about 10 months before (Oct. 15, '05),

My advice is needle no larger than 29ga and no longer than 1/2", unless you are lucky enough to be hung like a horse. Update- I injected trimix last night on my own for the first time, .33 cc of trimix with a .5 cc syringe with a 30g x 5/16 needle and it work very well, no pain at all and was quick.

It depends how well it was made and how you store it. Six months to two years give or take. Should be years if kept at 4C in distilled water. Spore syringes are generally 10E9-10E12 per mL. Efficiency in innoc site may decrease over time but you need logarithm decreases in viability. 90% is 1log, 99% is 2logs, 99.9% is 3logs.Checked Bags: Yes. Unused syringes are allowed when accompanied by injectable medication. You must declare these items to security officers at the checkpoint for inspection. We recommend, but do not require, that your medications be labeled to facilitate the security process. Learn more about transporting medication on your next flight.Trimix usually takes 5-20 minutes to achieve the maximum effects. If you do not get an erection after 20 minutes, do not inject more Trimix. Your dosage can be adjusted, but you should always wait at least 48 hours between injections. You may increase your dose by five units each time until you get the effect you want.Injecting too much TriMix can also cause priapism—a prolonged erection (we're talking four hours or more after sex), says Cheuck. Priapism happens when blood doesn't flow out of your penis. Your shaft may become rigid—although your tip stays soft—and pain will slowly progress. Priapism is uncommon, but it can happen if you get the ...By storing the mushroom spore syringes in the best possible conditions and taking precautions to avoid contamination, you can ensure the long-term viability and quality of the spores. In the next section, we will discuss the importance of monitoring and maintaining the spore syringes to prevent any issues during storage.The injections available through our laboratory include: (1) BI-MIXTURES - various combinations containing two commonly used vasodilators for ED. (2) TriMIX MIXTURES - Triple combination therapy was first introduced in 1991 by Bennett and his colleagues who demonstrated a success rate of TriMix of 92% in 116 patients using this combination ...TriMix Laboratories today announced KRS Global Biotechnology has conducted testing on TriMix-gel compounds which allow the expiration date for patient usage to be extended to 60 days.

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To keep your trimix cold while traveling, use a portable insulated cooler. This will maintain the right temperature and ensure the medication's effectiveness and safety during your trip. When traveling with Trimix, it's crucial to prioritize its temperature control. Trimix is a medication commonly used for erectile dysfunction, which consists…Demonstration on reconstituting Trimix. Scroll down to watch the video. Any questions, email us at hello@ ... the powder and Bacteriostatic Water. Wipe the tops with the alcohol swabs and let dry. Using the provided mixing syringe tighten the needle to the hub then pull back the plunger to the amount directed, usually 5ml/cc, and insert the ...There is now convincing evidence that cleaning syringes with water and bleach will kill ALL of the blood-borne virus in 99.9% of syringes. This short documentary talks to the research team who conducted the research on the impact of bleach on HIV on syringes, and explains why it is so important that syringe cleaning is taught to injecting drug ...This figure should be reassuring for those who are worried about how long the vial is out of the fridge while they draw their shot, or even for those men who are concerned about the filled syringe sitting there in the toothbrush holder during the several hours of begging and pleading that passes for foreplay sometimes. An unrefrigerated hour ... Q16. I’ve heard that Sudafed and Benadryl as well as Terbutaline can reduce a prolonged erection. When should these be used? A16. If the erection lasts more than 2 hours. If it is still a problem after 4 hours call your doctor or go to the emergency room. Q17. Can I use an ice pack to reduce an erection? Where and how should it be applied? A17. Mar 30, 2020 · I usually preload a syringe, and put it in a small thermos the night before. I keep the thermos in the bathroom, and will keep the Trimix for at least 24 hours at a temp. where it doesn’t deteriorate. When I go to get ready this saves time, and saves my wife. having to having to see my prep. The shelf life of trimix in the refrigerator can vary depending on various factors such as the gas mixture and storage conditions. Generally, trimix can last for approximately 3 to 6 months when stored in the refrigerator within the recommended temperature range. 3. What happens if trimix is stored for too long in the refrigerator? Hi, this forum is worth its weight in gold to me; I have tried trimix 3 times and I'm trying to figure out how many 'jabs' I'll get from a 5ml bottle; I measure up to 20 on my syringe; I've been told on here that its 20 units; does 100 units equal 1ml?Draw air into syringe: Take the syringe out of the package and remove the protective cap from the needle. Hold the syringe upright, so that the needle faces the sky. Draw air into the syringe by pulling DOWN the plunger to the SAME DOSE that you will inject. Inject air into medication vial: Turn the syringe downward so the needle is facing the ...Remove the needle from the bottle, holding the barrel of the syringe. Gently swirl the bottle to mix the powder into the solution, turning it upside down to wet all the powder in the bottle. Use the mixture within 24 hours of mixing it. Follow the directions below, “How to draw your dose into the syringe." ….

Veteran porn star Peter North says staying hard is a challenge that most male porn stars will confront at some point in their career. "Everyone thinks it would be so easy to stay hard on set and ...Super Trimix is a sterile compounded medication that is filled by specialized compounding pharmacies. Since Super Trimix is custom formulated, it can be adjusted to better meet your needs. Trimix Strength: Papaverine HCl 30 mg/mL, Phentolamine Mesylate 1 mg/mL Prostaglandin E1 10 mcg/mL. Super Trimix strength: Papaverine HCl 30 mg/mL ...Mass spectrometry is an aspect of science that could finally put the steroid era of baseball to an end. Learn about mass spectrometry. Advertisement ­The worlds of analytical chemi...Trimix works well for many guys. It's true that it's not "spontaneous," but waiting an hour or so for Viagra to kick in isn't spontaneous either. Your life is not over, concentrate on becoming a man who is kind and self assured so that people love to be around you. Best wishes. 3.Penile injections can help you achieve an erection with you have erectile dysfunction (ED). Skip to chief main. Prepare to start planning your care? Call us at 800-525-2225 to make an appointed. Sloan Kettering College; Research. Changing how the world understands and special cancer. Our scientists pursue every quality of cancer research—from ...When I get a new vial i draw up all the syringes and put them in a plastic container in the freezer. When I'm ready for happy time I set out a syringe for 20-30 minutes and I'm ready to go. I don't like ruining any spontaneous foreplay having to draw up the syringe. I really wish I used my vial faster, too.Jun 15, 2022 · The alprostadil in Trimix can weaken over time, so Trimix should be stored in the refrigerator and away from light. This can keep the medication good for a few additional months. If you’re using Bimix or papaverine, you don’t need to keep the medication in your refrigerator because these medications don’t contain alprostadil. Q12. Can injections be used with vacuum erection devices? A12. DO NOT use a vacuum erection device after injecting! Serious bleeding can result. There may be exceptions. Please consult your doctor. Q13. My medication requires refrigeration. How long can it be left un-refrigerated? A13. Three hours Q14. TriMix injections usually provide an erection that lasts no longer than an hour. Self-injection into the penis is recommended a maximum of two to three times per week, and never more than once in any 24 hours. Dropping testosterone levels doesn't have to become a problem for you. To find out more about testosterone replacement therapy, or to ... How long can i keep trimix in a syringe, 1st injection: try 0.1ml (or 10 units as marked on the side of the syringe). If this is not successful, do not give yourself a second injection. Wait a minimum ..., My 5ml of Trimix lasts 5-6 weeks so there is no need for me to freeze the vial, It stays good for 90 days refrigerated. I did speak to a patient once who said he filled syringes and froze them, I have never tried that though. I did ask my Dr about taking an oral med with the Trimix, and he said it defeats the purpose., Oct 7, 2021 · Remove the syringe and press an alcohol pad or gauze on the site after the injection for at least five minutes (or up to 10 minutes if you are on a blood thinner, such as Coumadin). If you prefer, you can use an auto-injector, which is a spring-loaded device that inserts the needle into the penis very quickly, minimizing discomfort. , Freezing Temperature: Trimix should be stored at a temperature between 23 degrees to -70 degrees Celsius. This temperature range ensures the stability of the medication. Duration of Freezing: It is generally recommended not to freeze Trimix for more than two months. Prolonged freezing can lead to an imbalance in the dosage and a decrease in ..., People should not pre-fill one of the most widely used brand of syringe, because whatever drug is in there might lose its potency, the FDA says. The FDA warns not to leave drugs sitting in Becton ..., I think you can find older posts on this site with other guys who will say the same thing. My drill is to thaw the vial and fill three or four syringes every week. The vial then goes back into the freezer. The syringes go in the refrigerator until use. To thaw the vial, I just let it sit out for 15-20 minutes., Point needle to the center, not up or down. Alternate sides of injection to avoid scaring tissue. Lay your penis flat out and fully extended (but soft) Avoid veins. Target the area 1 inch up from the base between 1 to 2:30 o'clock ( or 9:30 to 11) Work the plunger a few times before filling syringe to insure it is not sticky., Art by Jeanne Koelling with input from Maurice Garcia, MD, MAS; Tom F. Lue, MD, ScD (Hon), FACS and advocate Stan Rosenfeld. 2 #FTJEFTUIF BOE PDMPDLQPTJUJPOT *hWFBMTPCFFOUPMEUIBU*DBOJOKFDUBU PhDMPDLQPTJUJPOT %PFTJUNBUUFS. " BOE BSFBMM0, CVU BOE BSFUIFCFTU. BOE., The shelf life of trimix in the refrigerator can vary depending on various factors such as the gas mixture and storage conditions. Generally, trimix can last for approximately 3 to 6 months when stored in the refrigerator within the recommended temperature range. 3., If you don't want to lose a bit you should leave a several-unit bubble in the syringe and freeze them needle-up. I figured all this out when I noticed that 35 units of frozen trimix turned into 32 units when re-thawed. SUCCESS WITH FROZEN TRIMIX!I am 38 months out from DaVinci RP and have been using Trimix since month 8., The FrankTalk.Org website strives to advance patient education about Erectile Dysfunction, what programming language does rockstar use; gportal terraria server. industrial real estate developers; pa temporary license expired; people in charge crossword clue, It's a long story on how we got there, but we went from regular trimix strength to trimix-2 and used too high of a dosage. We think the initial problem of the regular trimix was that it was losing it's potency (getting old or we let it get warm somehow). We thought it wasn't working. Doc gave us a brand new bottle of trimix-2., By 'off', I mean crystals or too cloudy. As for the bubble, when 1st making the dosage, siphon off a bit more, then depress plunger to get any air bubbles out (tap/flick the syringe to get air bubbles to go to the top). The bubbles will not kill you, but it is recommended, just in case. Ag, 58, Maryland., Even with tough safety regulations for flying in place, it is possible to carry needles or syringes onboard an aircraft cabin. Diabetes is just one condition which may require travelers to bring medicine, syringes, and needles on a flight. If you have a condition which requires that you inject yourself with medication, prior to travel ask your ..., Posted 8/2/2011 12:56 PM (GMT -8) Hey WDF4 and Water Guy, I had not heard that Trimix becomes ineffective after 100 to 150 injections. Indeed, on another forum a fellow stated he had used it for seven years. I am over 150 injections and have not noticed any decrease in the effectiveness of Trimix., According to the USDA, cooked salmon can be safely stored in the refrigerator for up to 3 to 4 days. However, it is important to note that the quality of the salmon may start to deteriorate after the first day. To extend its shelf life, you can also freeze the cooked salmon, and it can last for up to 2 months., At Renew Vitality, our team of doctors will thoroughly review your medical history to accurately design an individualized TriMix regimen that is safe and effective in helping you treat erectile dysfunction. Call us at 1-800-785-3945 to schedule an appointment at any of our hormone replacement clinics in the United States., Anyone interested in learning more about TriMix-gel can visit www.TriMixgel.com. KRS Customer Care Managers are available at 888-368-1990. KRS Customer Care Managers are available at 888-368-1990., This allows for greater blood flow into the penis. For more information about Trimix urethral gel, call us now at (204) 233-3469 , email us at [email protected] or visit our contact us page for other methods of contact such as our online contact form. If you were looking for information about our Trimix injections please visit our ED injections page., Cold insulin will release air bubbles as it warms up. If you draw a syringe then wait for it to warm up you'll see small "champagne" bubbles have collected in the syringe. This is an issue for insulin pumps where you draw about 3 days worth of insulin into a resevoir. I don't know if the same is true for trimix/bimix., minutes. Keep upright for 10-15 minutes. 6. Place the syringe in a container to be disposed. 2. Find the injection site and clean it with an alcohol wipe. Grip the head of the penis. Hold the penis on the side of your thigh. 3. Hold the syringe between the thumb and middle finger. Inject the needle at the injection site at a 90-degree angle. 4., It is recommended to keep Tri-mix either refrigerated or frozen for two reasons. The main reason is to maintain sterility. Every time the vial is pierced by the needle, bacteria and/or viruses can enter. Keeping the liquid refrigerated or frozen, dramatically slows the growth from these pathogens. Secondly, alprostadil degrades rapidly at room ..., it from light (keep in original packaging). Monitor refrigerator temperature using a digital thermometer with the probe inserted in a vial of biosafe glycol or a vial of glass beads. Tuberculin that has been exposed to freezing temperatures (32º F or lower) or has been stored above 46ºF should be discarded., Wipe rubber stopper with alcohol swab and allow to dry. 3. Remove safety cap from syringe and insert into vial. 4. Draw up designated dose and remove any air bubbles. 5. Clean injection site with alcohol swab. 6. Inject Trimix solution into the cavernosal muscle slowly until syringe is empty and safely discard syringe., It depends how well it was made and how you store it. Six months to two years give or take. Should be years if kept at 4C in distilled water. Spore syringes are generally 10E9-10E12 per mL. Efficiency in innoc site may decrease over time but you need logarithm decreases in viability. 90% is 1log, 99% is 2logs, 99.9% is 3logs., Mar 22, 2023 · How long can Trimix last in a syringe? Trimix can last in a syringe for a limited period, typically ranging from a few hours to a day, depending on factors such as temperature and storage conditions. However, it’s important to use Trimix promptly after preparation to ensure potency and safety. , Pros: I've been using it for several years with 90-95 % success rate and can count on one hand the number of times I didn't inject properly or deep enough into the corpora ,plus one time when I was a little too high while injecting and nicked a capillary withdrawing the syringe and bled like hell from my urethra., An insulin syringe varies in sizes from 0.25 ml to 1.0 ml. The syringe size indicates the number of units it can hold. So a 0.40 ml can hold 40 units of insulin. The larger the syringe size, the more insulin unit it can hold. When it comes to choosing the perfect size of syringe, you have to keep in mind the following:, School Uniforms; Media. Gallery; School Events; Newsletter; School Policies; Contact Us, This article explores how long can you keep trimix in a syringe. We will look at factors that affect the shelf life of trimix, how to determine the expiration date, and tips for maximizing the usage of your trimix injections. Additionally, we will discuss best practices when it comes to storage and disposal, as well as the do's and don'ts of maintaining trimix in a syringe., TriMix is safe even for those with diabetes, heart problems, circulation issues, or a history of prostate surgery or cancer. How long do the results last? Erections from a TriMix injection usually last between one and two hours. If they exceed two hours, an antidote, phenylephrine, can be applied in a similar manner to TriMix., When on vacation I sometimes cannot refrigerate my pre-filled trimix syringes. I find very little loss of potency during the first week. By 2 weeks without refrigeration I have to increase the dose by about 50% to get adequate results. The trimix that I get says that I should store the vial frozen.